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SPRING SCHOOL PROGRAMME

Check the programme regularly for updates

Tue

Tuesday 16 April

15:00-16:00
Registration

16:00-18:30
Workshops (40 students per workshop)

16:00-18:30
Workshop 1: Connecting Science and Society: Communicating Your Work Beyond the Lab
Anna Couturier, EuroGCT

16:00-18:30
Workshop 2: How to write a scientific manuscript
Thomas Gallagher, Human Gene Therapy

16:00-18:30
How to judge a scientific publication
Hildegard Büning, Hannover Medical School

19:30
Meet the expert dinner @ Araz Restaurant, Continental Hotel

H-1074 Budapest, Dohány utca 42-44.

Wed

Wednesday 17 April

08:30-09:00
Welcome Address
Juan Bueren (President, ESGCT)
Zoltan Ivics (Spring School Host and co-organiser; President elect DG&GT)
Hildegard Büning (ESGCT Education & Training)

09:00-10:00

Keynote
INV01: Juan Bueren, Ciemat Madrid
Moving from Concept to Clinical Reality 

10:00-11:30

Session 1: Gene therapy tools - insights by experts (Viral Vectors)
INV02Axel Schambach, Hannover Medical School
What you should know about retro/lentiviral vector design
INV03Els Verhoeyen, University of Nice
How to improve nature I – the next generation of lentiviral vectors
INV04: Jacob Giehm Mikkelsen, Aarhus, Denmark
Engineered lentivirus-derived particles for delivery of gene editing tool kits

11:30-12:00
Coffee Break

12:00-13:00
Keynote
INV05Fulvio Mavilio, Orchard Therapeutics
Hematopoietic stem cell gene therapy for genetic diseases

13:00-14:00
Lunch

14:00-17:00
Session 2: Gene therapy tools - insights by experts (Viral vectors)
INV06: Hildegard Büning, Hannover Medical School
Almost a virus – the adeno-associated virus (AAV) vector system vector design
INV07: Alberto Auricchio, Tigem Naples
ExpEditing AAV gene therapy
INV08: Luk Vandenberghe, Harvard Medical School 
AAV-as a vaccine platform

17:00-17:30
Coffee Break

17:30-19:30
Session 3: Gene therapy tools - insights by experts (non-viral vectors)
INV10: Tristan Montier, University of Brest
How to fine tune nanoparticles for aerosol delivery?
INV11: Raymond SchiffelersUMC Utrecht
Lipid nanoparticles and their applications in vaccination and beyond
INV12: Zoltan Ivics, Paul Ehrlich Institute, Langen
Wide awake and ready to move: non-viral genome engineering with Sleeping Beauty transposon vectors

20:00
Dinner at Ruin Bar Extra with DJ and surprise

Extra Brunch Bar Club
H-1072 Budapest, Klauzál u. 15.

Directions from the venue
Take trams 4 or 6 back towards the center of town
Exit at Blaha Lujza (6 stops)

From there it is a 5 minute walk and only around the corner from the Continental Hotel where the dinner took place yesterday.

Thu

Thursday 18 April

09:00-10:00
Keynote
INV13Toni Cathomen, University Hospital, Freiburg
Revelations in Precision: Learning from On- & Off-Target Effects of Gene Editing Tools

10:00-10:30
Coffee Break

10:30-12:30
Session 4: Genome and epigenome editing
INV14: Paula Rio, Ciemat, Madrid
Gene editing with CRISPR and beyond
INV15: Claudio Mussolino, University of Freiburg
Multiplexed epigenome editing in CAR T cells

INV16: Gloria Gonzalez-Aseguinolaza, Fima, Pamplona
AAV for in vivo gene editing to treat rare liver diseases

12:30-13:30
Lunch

13:30-15:30
Session 5: iPSC technology
INV17: Agota Apati, Research Centre for Natural Sciences, Budapest
Advancements in induced pluripotent stem (iPS) technology and two-dimensional disease models
INV18: Kornelia Szebenyi, Research Centre for Natural Sciences, Budapest
Human induced pluripotent stem cell-derived organoids for disease modeling
INV19: Andras Nagy, Lunenfeld-Tanenbaum Research Institute, Toronto
Therapeutic applications

15:30 -16:30
Keynote
INV20: Nathalie Cartier, AskBio, Paris
Gene therapy for CNS diseases : strategies, hurdles, results

16:30-17:00
Coffee Break

17:00-17:40
Session 6: Fighting cancer with novel weapons
INV21: Hinrich Abken, University of Regensburg
CARs, TRUKCKs and what is next? - The evolution of CAR T cell therapy

17:40 -18:40
Keynote
INV22: Vincenzo Cerullo, University of Helsinki
Dressing viruses in tumor’s clothing – new strategies in anti-tumor therapy

19:00
Boat trip on the Danube with dinner and DJ

Fri

Friday 19 April

09.00-10.00
Keynote
INV23: Anne Galy, Inserm ART-TG laboratory
Immune system: friend or foe in gene therapy.

10.00-10.30
Coffee Break

10:30-12.30
Session 7: Pre-clinical and clinical gene therapy
INV24: Giuliana Ferrari, SR Tiget, Milan
Gene therapy for hemoglobinopathies: past, present and future
INV25Federico Mingozzi, Nava Therapeutics
Translating in vivo gene therapies from bench to bedside
INV26: Fatima Bosch, UAB, Barcelona
A new horizon in gene therapy: Moving from the treatment of rare to highly prevalent diseases


12:30-13.30

Keynote
INV27: Claire Booth, UCL London
It is all about accessibility

13:30
Closing
Alberto Auricchio, Hildegard Büning & Zoltan Ivics

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